TABLE 3.
Associations Between Center Clinical Deterioration Event Mortality and Center Characteristics
| Center Characteristic | Correlation Coefficient | OR (95% CI) | P | Adjusted P a |
|---|---|---|---|---|
| UMIC/HIC vs LIC/LMIC | −0.0737 | 0.93 (0.58‐1.49) | .7606 | .7606 |
| Pediatric hospital vs all ages | −0.1734 | 0.84 (0.57‐1.23) | .3743 | .401 |
| Oncology hospital vs pediatric/general multidisciplinary | −1.0345 | 0.36 (0.24‐0.52) | <.0001 | <.0001 |
| Total PHO hospital patient‐days: June 2017 to May 2018 | −0.0431 | 0.96 (0.94‐0.98) | <.0001 | <.0001 |
| No. of annual new pediatric cancer diagnoses | −9.00E‐04 | 0.999 (0.998‐1) | .045 | .0562 |
| No. of PHO beds | −0.0261 | 0.97 (0.96‐0.98) | <.0001 | <.0001 |
| No. of PICU beds | 0.0537 | 1.06 (1.02‐1.09) | .0004 | .0007 |
| Case mix, % of events with leukemia | −0.7872 | 0.46 (0.11‐1.93) | .283 | .3265 |
| Average floor nursing ratio: 1 nurse/x patients | 0.1251 | 1.13 (1.07‐1.20) | <.0001 | <.0001 |
| Rate of floor interventions per 1000 patient‐days | 0.1283 | 1.14 (1.01‐1.27) | .0278 | .0379 |
| Rate of floor cardiopulmonary arrest per 1000 patient‐days | 0.3822 | 1.46 (1.24‐1.72) | <.0001 | <.0001 |
| PEWS implemented at start of study period | −1.2685 | 0.28 (0.19‐0.42) | <.0001 | <.0001 |
| Percentage of CDEs with transfer to higher level of care b | −2.1371 | 0.12 (0.2‐0.76) | .024 | .036 |
| Median PIM2 on PICU admission b | 0.9396 | 2.56 (2.01‐3.26) | <.0001 | <.0001 |
| Median no. of organs with dysfunction on transfer | 0.2138 | 1.24 (1.16‐1.37) | <.0001 | <.0001 |
Abbreviations: CDEs, clinical deterioration events; HIC, high‐income country; LIC, low‐income country; LMIC, low‐middle–income country; OR, odds ratio; PHO, pediatric hematology‐oncology; PEWS, Pediatric Early Warning System; PICU, pediatric intensive care unit; PIM2, Pediatric Index of Mortality 2; UMIC, upper‐middle–income country.
a
P values were adjusted for the false‐discovery rate.
b
These included 15 centers with ICUs.