Table 1.

Common nomenclature reporting HLA types

Name	Typing	Resolution	Nomenclature
Broad serology	Phenotyping (lymphocytotoxicity)	Low	B14
Split serology	Phenotyping (lymphocytotoxicity)	Low	B64 B65
First-field	Genotyping (PCR SSP)	Low	B*14
NMDP code	Genotyping (PCR SSO)	Intermediate	14:HUJ
Second-field	Genotyping (Sanger sequencing and/or NGS)	High	B*14:01 B*14:02

Note: HLA alleles nomenclature established by the World Health Organization Nomenclature Committee (http://hla.alleles.org/nomenclature/committee.html). Nomenclature is regularly updated. Here, we consider HLA-B*14:01:01 as an example. ‘NMDP codes’ allele codes narrow the list of alleles that must be considered at a given locus by eliminating some possibilities (e.g. B*14:HUJ means that the typing is either B*14:01 or B*14:02). ‘NMDP codes’ are implemented and updated by the NMDP (https://bioinformatics.bethematchclinical.org/hla-resources/allele-codes/allele-code-lists/allele-code-list-in-alphabetical-order/). PCR SSO: sequence specific oligonucleotide. PCR SSP: sequence specific primers (Howell et al., 2010).