Table 2.
Fertility evaluation before and after matching.
| Unmatched |
Matched |
|||||
|---|---|---|---|---|---|---|
| Control n = 3973 | Case n = 70 | P value | Control n = 195 | Case n = 65 | P value | |
| FSH (IU/L) | 7.5 (6.3, 9.1) | 7.6 (6.5, 9.0) | 0.828 | 7.6 (6.4, 9.3) | 7.5 (6.4, 9.1) | 0.644 |
| AMH (ng/mL) | 2.6 (1.3, 4.6) | 2.7 (1.3, 4.7) | 0.789 | 2.5 (1.1, 4.3) | 2.8 (1.5, 4.9) | 0.247 |
| AFC | 10.0 (6.0, 16.5) | 10.0 (5.0, 18.0) | 0.750 | 10.0 (6.0, 17.0) | 10.0 (7.0, 18.5) | 0.151 |
| Gn duration (days) | 9.0 (8.0, 11.0) | 10.0 (8.0, 11.0) | 0.092 | 10 (9.0, 11.0) | 10.0 (8.0, 11.0) | 0.276 |
| Gn dosage (IU) | 2400.0 (1800.0, 3000.0) | 2475.0 (1873.1, 3084.4) | 0.362 | 2437.5 (1897.5, 3075.0) | 2400.0 (1848.8, 3056.3) | 0.914 |
| NO. of large follicles on HCG day | 9.0 (5.0, 13.0) | 9.0 (5.0, 13.3) | 0.761 | 9.0 (5.0, 13.0) | 9.0 (5.5, 14.0) | 0.322 |
| NO. of oocytes retrieved | 11.0 (6.0, 16.0) | 11.0 (5.0, 14.0) | 0.352 | 11.0 (5.0, 16.0) | 11.0 (6.0, 14.5) | 0.804 |
| Ovarian response grading1 | 0.696 | 0.666 | ||||
| Adequate | 46.6 (1853) | 44.3 (31) | 44.6 (87) | 47.7 (31) | ||
| Poor | 53.4 (2120) | 55.7 (39) | 55.4 (108) | 52.3 (34) | ||
Note:
FSH, follicle stimulation hormone; AMH, anti-Müllerian hormone; AFC, antral follicle counting; Gn, gonadotropin; HCG, human chorionic gonadotrophin.
Continuous variables were presented as the median (first quartile, third quartile).
Categorical variables were presented as% (n).
1 The ovarian response grading was based on the POSEIDON classification.