Skip to main content
. 2021 Jun 7;595(7866):278–282. doi: 10.1038/s41586-021-03676-z

Fig. 4. Structures of leading nanobodies in complex with SARS-CoV-2 spike.

Fig. 4

a, Cryo-electron microscopy structure of Nb12 in complex with SARS-CoV-2 spike. b, As in a, for Nb30. c, Interface between nanobodies and spike. d, Surface properties of RBD, including sequence diversity (dark purple indicates diversity among sarbecoviruses), and prevalence of RBD-recognized regions by human antibodies (dark raspberry indicates high prevalence) and binding site for ACE2 (cyan).