Table 1.
Participant characteristics at screening appointment.
| Placebo |
Dexamethasone |
|||
|---|---|---|---|---|
| N | 27 | 80 | ||
| Median [min, Q1, Q3, max]* | Median [min, Q1, Q3, max]* | |||
| Age (years) | 43 [21, 38, 46, 53] | 43 [21, 37·5, 47, 54] | ||
| Response when asked how long HMB has been a problem (years) | 5 [1, 3, 11, 33] | 5 [0·5, 2, 14, 37] | ||
| Minimum duration of menses in previous 3 months (days) ⁎⁎ | 5·5 [3, 5, 7, 15] | 5·0 [2, 4, 6, 14] | ||
| Maximum duration of menses in previous 3 months (days) ⁎⁎ | 7 [4, 6, 8, 21] | 7 [3, 5, 7, 15] | ||
| Mean screening menstrual blood loss (mL) | 112·0 [51, 63·5, 206, 677·5] | 136·0 [50, 84, 187, 479·5] | ||
| Approx. years since last pregnancy (if applicable⁎⁎⁎) | 6 [2, 5, 9, 24] | 11 [0, 6, 15, 31] | ||
| Weight (kg) | 69·2 [48, 60·9, 91, 129] | 74·4 [46, 64·8, 85·2, 124] | ||
| Units of alcohol consumed per week currently | 1 [0, 0, 6, 16] | 3 [0, 0·5, 10, 40] | ||
| Mean (SD) | Mean (SD) | |||
|---|---|---|---|---|
| Age at menarche (years) | 12·6 (1·4) | 12·8 (1·5) | ||
| Systolic blood pressure (mmHg) | 122·0 (13·4) | 124·9 (12·3) | ||
| Diastolic blood pressure (mmHg) | 76·1 (13·3) | 77·2 (10·1) | ||
| Minimum cycle length past 3 months (days) | 26·4 (2·7) | 26·0 (2·6) | ||
| Maximum cycle length past 3 months (days) | 30·5 (4·4) | 29·8 (3·5) | ||
| Placebo |
Dexamethasone |
|||
|---|---|---|---|---|
| N | 27 |
80 |
||
| n | % | n | % | |
| Ethnicity | ||||
| White | 26 | 96% | 73 | 91% |
| Mixed | 0 | 1 | 1% | |
| Asian | 0 | 3 | 4% | |
| African | 1 | 4% | 1 | 1% |
| Caribbean | 0 | 1 | 1% | |
| Not disclosed | 0 | 1 | 1% | |
| No. of births | ||||
| None | 10 | 37% | 25 | 31% |
| 1 | 3 | 11% | 16 | 20% |
| 2 | 9 | 33% | 22 | 27% |
| 3 | 4 | 15% | 13 | 16% |
| 4–6 | 1 | 4% | 4 | 5% |
| No. of miscarriages | ||||
| None | 17 | 63% | 59 | 74% |
| 1 | 7 | 26% | 15 | 19% |
| 2–4 | 3 | 11% | 6 | 8% |
| No. of terminations | ||||
| None | 22 | 81% | 63 | 79% |
| 1 | 3 | 11% | 11 | 14% |
| 2 | 2 | 7% | 5 | 6% |
| 3 | 0 | 0 | ||
| 4 | 0 | 1 | 1% | |
| Response when asked if has painful periods | ||||
| Yes | 21 | 78% | 58 | 73% |
| No | 6 | 22% | 22 | 27% |
| Fibroids present | ||||
| No recent USS/MRI | 1 | 4% | 5 | 6% |
| No fibroids detected | 16 | 59% | 41 | 51% |
| Fibroid < 3 cm | 8 | 30% | 25 | 31% |
| Fibroid >= 3 cm | 2 | 7% | 9 | 11% |
| Smoking history | ||||
| Current (1 to 20 per day) | 6 | 22% | 8 | 10% |
| Previous | 3 | 11% | 19 | 24% |
| Never | 18 | 67% | 53 | 66% |
⁎
min = minimum, Q1 = 1st quartile, Q3 = 3rd quartile, max = maximum.
⁎⁎
2 with missing data, one Placebo, one dexamethasone.
⁎⁎⁎
78 women had been pregnant, with 19 allocated to placebo, and 58 to Dexamethasone.