FIG 5.

Demineralization of human enamel surface by S. mutans-C. albicans biofilms with or without β-mannanase treatment. (A) Schematic diagram for human enamel slab preparation. Shown are representative confocal surface-topography of intact enamel (B), enamel after forming biofilms without β-mannanase treatment (C), and enamel after forming biofilms with β-mannanase treatment (D). Panels (C) and (D) were scanned after removing biofilms from the enamel. (E) Average surface roughness values of intact enamel slabs and slabs that had biofilms with or without β-mannanase treatment; ***, P < 0.001.