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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Nature. 2021 Jun 9;595(7866):303–308. doi: 10.1038/s41586-021-03633-w

Fig. 2 |. NORAD induces PUM phase separation through multivalent RNA binding.

Fig. 2 |

a-e, Confocal images (a, c) or turbidity measurements (absorbance at 600 nm, A600) (b, e) of 150 nM PUM1 solutions in the presence of increasing concentrations of the indicated RNAs or FAM-labeled PRE-containing RNA oligonucleotides (d). Turbidity normalized to A600 at 0 nM RNA (3 replicates per RNA concentration). Red box, consensus PRE; blue box, mutant PRE.