Table 4.
Collection of experimentally obtained values of phenacetin solubility in binary solvents along with the standard uncertainty (n = 3) expressed in mole fractions (×104). First column characterizes concentration of organic solvent in solute free solutions (x2* denotes mole fraction of organic solvent in solute free binary aqueous mixture).
| x2* | 298.15 | 303.15 | 308.15 | 313.15 |
|---|---|---|---|---|
| acetonitrile + water | ||||
| 0.2 | 25.9 ± 1.0 | 34.5 ± 0.5 | 46.0 ± 1.7 | 62.8 ± 2.3 |
| 0.4 | 90.1 ± 2.9 | 107.3 ± 4.2 | 132.8 ± 4.6 | 165.4 ± 4.7 |
| 0.6 | 173.6 ± 5.0 | 202.9 ± 6.2 | 246.3 ± 2.9 | 300.3 ± 6.2 |
| 0.8 | 180.8 ± 3.0 | 216.7 ± 5.2 | 269.2 ± 5.4 | 336.2 ± 11.7 |
| 1,4-dioxane + water | ||||
| 0.2 | 55.7 ± 2.3 | 64.2 ± 2.6 | 79.2 ± 1.9 | 99.9 ± 1.7 |
| 0.4 | 379.5 ± 12.7 | 433.2 ± 14.9 | 508.1 ± 7.0 | 616.1 ± 8.7 |
| 0.6 | 446.3 ± 13.0 | 504.2 ± 13.1 | 600.0 ± 8.3 | 739.8 ± 14.5 |
| 0.8 | 302.1 ± 7.9 | 358.0 ± 11.7 | 427.6 ± 9.7 | 510.7 ± 10.6 |
| 0.0 | 0.9 ± 0.0 | 1.1 ± 0.1 | 1.5 ± 0.0 | 2.1 ± 0.1 |
| DMF + water | ||||
| 0.2 | 13.8 ± 2.7 | 33.2 ± 2.1 | 61.1 ± 1.9 | 105.2 ± 3.0 |
| 0.4 | 106.6 ± 4.7 | 138.8 ± 4.7 | 183.4 ± 4.6 | 252.8 ± 4.5 |
| 0.6 | 199.3 ± 10.9 | 268.2 ± 8.8 | 364.7 ± 11.8 | 498.6 ± 9.7 |
| 0.8 | 315.7 ± 16.5 | 434.3 ± 24.7 | 591.2 ± 20.6 | 791.5 ± 14.8 |
| DMSO + water | ||||
| 0.2 | 7.2 ± 0.3 | 10.6 ± 0.5 | 15.0 ± 0.3 | 19.7 ± 0.7 |
| 0.4 | 70.5 ± 2.5 | 85.6 ± 1.1 | 102.7 ± 1.8 | 121.9 ± 2.7 |
| 0.6 | 200.5 ± 3.2 | 243.4 ± 8.8 | 297.6 ± 2.4 | 358.4 ± 6.6 |
| 0.8 | 290.2 ± 15.0 | 407.4 ± 19.7 | 552.7 ± 7.7 | 741.8 ± 15.9 |
| MeOH + water | ||||
| 0.2 | 5.1 ± 0.5 | 7.3 ± 0.6 | 10.4 ± 0.5 | 14.7 ± 0.5 |
| 0.4 | 18.8 ± 0.5 | 22.6 ± 0.9 | 28.3 ± 0.4 | 35.2 ± 1.0 |
| 0.6 | 74.6 ± 1.7 | 84.0 ± 3.5 | 97.4 ± 4.5 | 122.1 ± 1.1 |
| 0.8 | 142.6 ± 4.0 | 167.5 ± 5.5 | 210.0 ± 2.5 | 264.2 ± 6.5 |