Monoclonal antibody therapies hold great promise for COVID-19; however, the recent emergence and spread of escape variants threaten to limit their value. Shown here are structural and linear representations of key escape mutations in the spike protein of SARS-CoV-2 and the latest information on the impact of variants of concern. To view this SnapShot, open or download the PDF.
. 2021 Jul 14;29(7):1162–1162.e1. doi: 10.1016/j.chom.2021.06.005
SnapShot: SARS-CoV-2 antibodies
David C Montefiori
1,2, Priyamvada Acharya
1,2
David C Montefiori
1Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA
2Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA
Find articles by David C Montefiori
Priyamvada Acharya
1Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA
2Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA
Find articles by Priyamvada Acharya
1Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA
2Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA
Issue date 2021 Jul 14.
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PMCID: PMC8279512 PMID: 34265246