Abstract
Trophozoites, gametes, and schizonts characteristic of Cryptosporidia were demonstrated in 2 Tanzanian goat kids. In a heavily infected kid the parasite was associated with villous atrophy and crypt hyperplasia. An enhanced epithelial cell ageing and extrusion rate, possibly due to a drain on cell metabolites by the parasite, is suggested. The protozoan seemed to induce host cell specializations, including parasitophorous envelope and development of smooth-membraned vesicles. The vesicles possibly have a function in the transport of nutrients from the host cell to the parasite.
Keywords: ultrasonics, dogs, bitches
Sammendrag
Hos Tranzanianske kje såes trophozoiter, gameter og schizonter med morfologi typisk for kryptosporidier. Hos ett dyr med massiv infeksjon fantes atrofi av tarmtottene og hyperplasi av kryptene. Et forkortet livsløp og forøket avstøtning av epitelcellene i tarmen ble satt i forbindelse med parasittenes forbruk av cellemetabolitter. Protozoene syntes å forårsake spesialiseringer hos vertscellen, bl. a. vakuoler som omgav parasittene og cytoplasmatiske vesikler. Vesiklene har kanskje betydning i transporten av metabolitter fra vertscellen til parasitten.
Full Text
The Full Text of this article is available as a PDF (1.7 MB).
References
- Angus K. W. Cryptosporidiosis in man, domestic animals and birds: a review. J. Roy. Soc. Med. 1983;76:62–70. doi: 10.1177/014107688307600114. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hampton J. C., Rosario B. The attachment of protozoan parasites to intestinal epithelial cells of the mouse. J. Parasit. 1966;52:939–949. doi: 10.2307/3276540. [DOI] [PubMed] [Google Scholar]
- Mason R. W., Hartley W. J., Tilt L. Intestinal cryptosporidiosis in a kid goat. Aust. vet. J. 1981;57:386–388. doi: 10.1111/j.1751-0813.1981.tb00529.x. [DOI] [PubMed] [Google Scholar]
- Meuten D. J., Van Kruiningen H. J., Lein D. H. Cryptosporidiosis in a calf. J. Amer. vet. med. Assoc. 1974;165:914–917. [PubMed] [Google Scholar]
- Moon H. W., McClurkin A. W., Isaacson R. E., Pohlenz J., Skartvedt S. M., Gillette K. G., Baetz A. L. Pathogenic relationships of rotavirus, Escherichia coli and other agents in mixed infections in calves. J. Amer. vet. med. Assoc. 1978;173:577–583. [PubMed] [Google Scholar]
- Panciera R. J., Thomassen R. W., Garner F. M. Cryptosporidial infection in a calf. Vet. Path. 1971;8:479–484. doi: 10.1177/0300985871008005-00610. [DOI] [Google Scholar]
- Pearson, G. R. & E. F. Logan: Scanning and transmission electron microscopic observations on the host-parasite relationship in intestinal cryptosporidiosis of neonatal calves. Res. Vet. Sci. 1983, 34 , 149–154. [PubMed]
- Pohlenz J., Bemrick W. J., Moon H. W., Cheville N. F. Bovine cryptosporidiosis: A transmission and scanning electron microscopic study of some stages in the life cycle and of the hostparasite relationship. Vet. Path. 1978;15:417–427. doi: 10.1177/030098587801500318. [DOI] [PubMed] [Google Scholar]
- Tzipori, S., K. W. Angus, L Campbell & E. W. Gray: Cryptosporidium: Evidence for a single species genus. Infect. Immun. 1980, 30, 884–886, [DOI] [PMC free article] [PubMed]
- Tzipori S., Larsen J., Smith M., Luefl R. Diarrhoea in goat kids attributed to cryptospiridium infection. Vet. Rec. 1982;111:35–36. doi: 10.1136/vr.111.2.35. [DOI] [PubMed] [Google Scholar]
- Tzipori S., Smith M., Halpin C., Angus K. W., Sherwood D., Campbell I. Experimental cryptosporidiosis in calves: Clinical manifestations and pathological findings. Vet. Rec. 1983;112:116–120. doi: 10.1136/vr.112.6.116. [DOI] [PubMed] [Google Scholar]
- Vetterling J. M., Takeuchi A., Madden P. A. Ultrastructure of Cryptosporidium wrairi from the guinea pig. J. Protozool. 1971;18:248–260. doi: 10.1111/j.1550-7408.1971.tb03316.x. [DOI] [PubMed] [Google Scholar]