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. 2021 Jun 9;10:182. Originally published 2021 Mar 5. [Version 2] doi: 10.12688/f1000research.28510.2

Figure 8. Chromatin accessibility and DNA methylation of vtRNA promoters in the Six Immune Subtypes analyzed in the PANCAN TCGA dataset.

Figure 8.

A. ATAC-seq values expressed as log2 normalized values for vtRNA promoters grouped in six Immune Subtype: wound healing (105 samples), IFN-g dominant (93 samples), inflammatory (110 samples), lymphocyte depleted (43 samples), immunologically quiet (9 samples), TGF-b dominant (4 samples). B. DNA methylation average beta-values for vtRNA promoters grouped in six Immune Subtype: wound healing (1963 samples), IFN-g dominant (2137 samples), inflammatory (2126 samples), lymphocyte depleted (933 samples), immunologically quiet (383 samples), TGF-b dominant (151 samples) ( Thorsson et al., 2018). The charts show the average and standard deviation for each vtRNA promoter in each Immune Subtype group.