to the editor: In a recent issue of the American Journal of Physiology-Heart and Circulatory Physiology, I read with great interest the rapid report, “Vascular alterations among young adults with SARS-CoV-2” (1). I have the following concern. Using the control group as healthy individuals misses the opportunity to show that vascular complications which are secondary to SARS-CoV2 infection is an exclusive effect of this viral infection. The group control should be individuals who recovered from other respiratory viral infections, e.g., influenza. In that way, we would have strong evidence that the vascular complications are secondary to SARS-CoV2 infection and not because they were recovering from an infection.
DISCLOSURES
No conflicts of interest, financial or otherwise, are declared by the author.
AUTHOR CONTRIBUTIONS
I.V. drafted, revised, and approved the final version of manuscript.
REFERENCES
- 1.Ratchford SM, Stickford JL, Province VM, Stute N, Augenreich MA, Koontz LK, Bobo LK, Stickford AS. Vascular alterations among young adults with SARS-CoV-2. Am J Physiol Heart Circ Physiol 320: H404–H410, 2021. doi: 10.1152/ajpheart.00897.2020. [DOI] [PMC free article] [PubMed] [Google Scholar]