Abstract
Diarrhea occurred in 12 pre-ruminant calves after the introduction of milk replacers. Six of the calves were fed a replacer made of normally treated skim milk and whey powder, while the other 6 got a replacer made of heat-treated powders, although otherwise similar to that of the first group. Abomasal curd formation was deficient in calves fed for 9 or 17 days on the heat-treated replacer (4 of 6 calves). Otherwise, no clear differences between the calves given normally treated and heat-treated replacer occurred, as regards diarrhea, bacteriological, virological, and pathomorphological findings in the intestinal tract. Rotavirus and chlamydial infections were indicated and considered as the major cause of the diarrheic condition, although bacteria, including coliforms and Pseudomonas aeruginosa, may have contributed. The milk replacers may have been involved was provoking factors.
Key words: heat-treatment, skim milk, whey, diarrhea, curd formation, intestinal microflora, rotavirus, chlamydia, calves
Sammendrag
Diaré opptrådte hos 12 unge kalver etter at de var satt på en melke-erstatningsdiett. Seks av kalvene fikk en erstatning läget av normalbehandlet myse- og tørrmelkspulver, de andre 6 fikk en til-svaren de diett, men hvor pulveret var varmebehandlet. Fire kalver som hadde fått varmebehandlet erstatning i henholdsvis 9 og 17 dager manglet løpekoagler. Ellers var det ikke sikre forskjeller mellom gruppene, hverken med hensyn til kvantitativt bakteriologiske, viro-logiske eller patomorfologiske funn i tarmkanalen. Rotavirus og chlamydier ble påvist hos noen av kalvene og betraktet som vesentlige år-saker til diaréen, selv om også koliforme bakterier og Pseudomonas aeruginosa kan ha bidratt. Melke-erstatningene kan ha spilt en rolle som provoserende faktorer.
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Footnotes
This study was supported by grants from the Agricultural Research Council of Norway.
References
- Appleman RD, Owen FG. Rreeding, housing and feeding management. J. Dairy Sci. 1975;58:447–464. doi: 10.3168/jds.S0022-0302(75)84588-7. [DOI] [Google Scholar]
- Blaxter KL, Wood WA. Some observations on the biochemical and physiological events associated with diarrhoea in calves. Vet. Rec. 1953;65:889–893. [Google Scholar]
- Bywater RJ. The functional pathology of neonatal diarrhoea in calves and piglets. Vet. Ann. 1975;15:425–431. [Google Scholar]
- Doughri, A. M., K. P. Altera, J. Storz & A. K. Eugster: Ultra-structural changes in the chlamydia-infected ileal mucosa of newborn calves. Vet. Path. 1973, 10, 114–123, [DOI] [PubMed]
- Doughri AM, Young S, Storz J. Pathologic changes in intestinal chlamydial infection of newborn calves. Amer. J. vet. Res. 1974;35:939–944. [PubMed] [Google Scholar]
- Emmons DB, Lister EE. Quality of protein in milk replacers for young calves. I. Factors affecting in vitro curd formation by rennet (chymosin, rennin) from reconstituted skim milk powder. Canad. J. anim Sci. 1976;56:317–325. doi: 10.4141/cjas76-037. [DOI] [Google Scholar]
- Laksesvela B, Slagsvold P, Landsverk T. Indigestion in young calves. III. The influence of powders from heat-treated skim and whey. Acta vet. scand. 1978;19:159–165. doi: 10.1186/BF03547621. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Landsverk T. The gastrointestinal mucosa in young milk-fed calves. A scanning electron and light microscopic investigation. Acta vet. scand. 1979;20:572–582. doi: 10.1186/BF03546585. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Landsverk T. Histochemical distribution of enzymes in the small intestine of young milk fed calves. Acta vet. scand. 1980;21:402–414. doi: 10.1186/BF03546873. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Landsverk, T.: The epithelium covering Peyer’s patches in young milk fed calves. An ultrastructural and enzyme histochemical investigation. Acta vet. scand. 1981a, 22, 198–210. [DOI] [PMC free article] [PubMed]
- Landsverk, T.: Pathomorphology of the intestinal mucosa in diarrheic calves. Acta vet. scand. 1981 b, 22, 435–448. [DOI] [PMC free article] [PubMed]
- Landsverk, T.: Peyer’s patches and the follicle-associated epithelium in diarrheic calves. Pathomorphology, morphometry and acid phosphatase histochemistry. Acta vet. scand. 1981c, 22, 459– 471. [DOI] [PMC free article] [PubMed]
- Lister EE, Emmons DB. Quality of protein in milk replacers for young calves. II. Effects of heat treatment of skim milk powder and fat levels on calf growth, feed intake and nitrogen balance. Ganad. J. anim. Sci. 1976;56:327–333. doi: 10.4141/cjas76-038. [DOI] [Google Scholar]
- Mebus CA, Stair EL, Underdahl NR, Twiehaus MJ. Pathology of neonatal calf diarrhea induced by a reo-like virus. Vet. Path. 1971;8:490–505. doi: 10.1177/0300985871008005-00612. [DOI] [Google Scholar]
- McNulty MS, McFerran JB, Bryson DG, Logan EF, Curran WL. Studies on rotavirus infection and diarrhoea in young calves. Vet. Rec. 1976;99:229–230. doi: 10.1136/vr.99.12.229. [DOI] [PubMed] [Google Scholar]
- Morin M, Lamothe P, Gagnon A, Malo R. A case of viral neonatal calf diarrhea in a Quebec dairy herd. Ganad. J. comp. Med. 1974;38:236–242. [PMC free article] [PubMed] [Google Scholar]
- Mylrea, P. J.: Digestion of milk in young calves. II. The absorption of nutrients from the small intestine. Res. Vet. Sci. 1966, 7, 394–416. [PubMed]
- Preston, T. R.: The nutrition of the early weaned calf. World. Rev. Nutr. Diet. 1964, 4, 121–139. [PubMed]
- Rexen, B. & B. Christensen: The determination of available lysine in feeding stuffs, automation in analytical chemistry. Technicon International Symposia 1966, 435–438.
- Rojas J, Schweigert BS, Rupel IW. The utilization of lactose by the dairy calf fed normal and modified milk diets. J. Dairy Sci. 1948;31:81–87. doi: 10.3168/jds.S0022-0302(48)92177-8. [DOI] [Google Scholar]
- Roy JHB. The nutrition of intensively-reared calves. Vet. Rec. 1964;76:511–526. [Google Scholar]
- Roy JHB. Diarrhoea of nutritional origin. Proc. Nutr. Soc. 1969;28:160–170. doi: 10.1079/PNS19690027. [DOI] [PubMed] [Google Scholar]
- Shillam KWG, Dawson DA, Roy JHB. The effect of heat treatment on the nutritive value of milk for the young calf. The effect of utra-hightemperature treatment and of pasteurization. Brit. J. Nutr. 1960;14:403–412. doi: 10.1079/BJN19600051. [DOI] [Google Scholar]
- Simensen E, Laksesvela B, Blom AK, Sjaastad ØV. Effects of transportations, a high lactose diet and ACTH infections on the white blood cell count, serum Cortisol and immunoglobulin G in young calves. Acta vet. scand. 1980;21:278–290. doi: 10.1186/BF03546890. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slagsvold P, Laksesvela B, Flatlandsmo K, Krogh N, Ulstein TL, Ek N, Landsverk T. Indigestion in young calves. I. Different lactose levels in milk diets and milk replacers. Acta vet. scand. 1977;18:194–209. doi: 10.1186/BF03548448. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith HW. Observations on the aetiology of neonatal diarrhea (scours) in calves. J. Path. Bact. 1962;84:147–168. doi: 10.1002/path.1700840117. [DOI] [PubMed] [Google Scholar]
- Stair EL, Mebus CA, Twiehaus MJ, Underdahl NR. Neonatal calf diarrhea. Electron microscopy of intestine infected with a reovirus-like agent. Vet. Path. 1973;10:155–170. doi: 10.1177/030098587301000208. [DOI] [PubMed] [Google Scholar]
- Tagari H, Roy JHB. The effect of heat treatment on the nutritive value of milk for the young calf. 8. The effect of the pre-heating treatment of spray-dried skim milk on the pH and the contents of total, protein and non-protein nitrogen of the pyloric outflow. Brit. J. Nutr. 1969;23:763–782. doi: 10.1079/BJN19690088. [DOI] [PubMed] [Google Scholar]
- Todd WJ, Doughri AM, Storz J. Ultrastructural changes in host cellular organelles in the course of the chlamydial development cycle. Zb. Bakt. Hyg. I. Abt. Orig. A. 1976;236:359–373. [PubMed] [Google Scholar]
- van Opdenbosch E, Wellemans G, Dekenel D, Strobbe R. Neonatal calf diarrhoea. A complex viral etiology. Vlaams Diergenees-kundig Tijdschrift. 1979;48:512–526. [Google Scholar]
- Walker DM, Faichney GJ. Nutritional diarrhoea in the milk-fed lamb and its relation to the intake of sugar. Brit. J. Nutr. 1964;18:209–215. doi: 10.1079/BJN19640020. [DOI] [PubMed] [Google Scholar]
- Ørstavik I, Figenschau KJ, Haug KWold, Ulstrup JC. A reovirus-like agent (rotavirus) in gastroenteritis of children. Virus detection and serological studies. Scand. J. infect. Dis. 1976;8:1–5. [PubMed] [Google Scholar]