Figure 5.

miR-361-3p inhibitors abrogated the regulatory effects of si-circRNA on WERI-Rb1 cells. (a) miR-361-3p expression was assessed in retinoblastoma cells post-introduction of miR-361-3p inhibitors and si-circRNA. (b) Colony formation assay revealed that miR-361-3p inhibitors abolished the roles of si-circRNA on WERI-Rb1 cells proliferation. (c, d) Wound healing and transwell assays showed si-circRNA-induced suppression of the migratory and invasive properties of WERI-Rb1 cells were reversed by miR-361-3p inhibitors. *p < 0.05.