Fig. 1.

Linalool inhibits HDMEC proliferation. a, b Viability (in % of 0 mM) of HDMECs (a) and cytotoxicity (in % of the total cell death) of linalool (b) as assessed by the WST-1 (a) and LDH assay (b), respectively. HDMECs were exposed for 24 h to serial dilutions (0.05–5 mM) of linalool or vehicle (0 mM) (n = 4). c: Flow cytometry scatter plots of HDMECs that were exposed for 24 h to 0.25, 1 and 2 mM linalool or vehicle (0 mM), incorporated with BrdU and then stained with FITC-conjugated anti-BrdU antibody. d BrdU-positive cells (in % of the total cell number) of vehicle- or linalool-treated HDMECs (n = 3). Means ± SEM. *P < 0.05 vs. 0 mM