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. 2021 Apr 27;70(8):1419–1425. doi: 10.1136/gutjnl-2019-319807

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Diagram showing different approaches to microbiota modulation for cancer treatment. The overall goal is to shift the tumour microenvironment from an immunosuppressive to an immune-activated state. FMT, faecal microbial transplant; MDSC, myeloid-derived suppressor cell; T_H1, type I helper; Treg, regulatory T cell.