Abstract
Serological examination of 4 Border disease affected flocks of sheep using the neutralization test showed antibody prevalences between 14 and 96 %. Prevalence in yearlings in 3 of the 4 flocks was 37 %, it increased with age to 72 % in 5-year-old sheep. Possible reason for low prevalence (2 %) in yearlings in one of the flocks is discussed.
Keywords: pestivirus, Border disease, bovine virus diarrhoea, sheep, serology, neutralizing antibodies
Sammendrag
Serologiske undersøkelser ved hjelp av nøytralisasjonstest i 4 sauebesetninger med Border disease viste antistoff prevalenser mellom 14 og 96 %. Prevalensen hos årsgamle lam i 3 av besetningene var 37 %, den økte med alder til 72 % hos 5 år garnie sauer. Mulig årsak til lav prevalens (2 %) for årsgamle lam i én av flokkene er diskutert.
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References
- Barlow R M, Rennie J C, Gardiner A C, Vantsis J T. Infection of pregnant sheep with the NADL strain of bovine virus diarrhoea virus and their subsequent challenge with Border disease IIB pool. J. comp. Path. 1980;90:67–72. doi: 10.1016/0021-9975(80)90029-8. [DOI] [PubMed] [Google Scholar]
- Barlow R M, Vantsis J T, Gardiner A C, Rennie J C, Herring J A, Scott F. M. M. Mechanisms of natural transmission of Border disease. J. comp. Path. 1980;90:57–65. doi: 10.1016/0021-9975(80)90028-6. [DOI] [PubMed] [Google Scholar]
- Done J T, Terlecki S, Richardson C, Harkness J W, Sands J J, Patterson D S P, Sweasey D, Shaw I G, Winkler C E, Duffel S J. Bovine virus diarrhoea-mucosal disease virus: Pathogenicity for the fetal calf following maternal infection. Vet. Rec. 1980;106:473–479. doi: 10.1136/vr.106.23.473. [DOI] [PubMed] [Google Scholar]
- French E L, Snowdon W A. Mucosal disease in Australian cattle. Aust. vet. J. 1964;40:99–105. doi: 10.1111/j.1751-0813.1964.tb01706.x. [DOI] [Google Scholar]
- Hamilton A F, Timoney P J. Bovine virus diarrhoea/mucosal disease virus and Border disease. Res. Vet. Sci. 1973;15:265–267. doi: 10.1016/S0034-5288(18)33839-6. [DOI] [PubMed] [Google Scholar]
- Harkness J W, Sands J J, Richards M S. Serological studies of mucosal disease virus in England and Wales. Res. Vet. Sci. 1978;24:98–103. doi: 10.1016/S0034-5288(18)33106-0. [DOI] [PubMed] [Google Scholar]
- Horzinek, M. C: Non-arthropod-borne Togaviruses. Academic Press, London 1981, pp. 77–85.
- Hughes L E, Kershaw G F, Shaw J G. “B” or Border disease. An undescribed disease of sheep. Vet. Rec. 1959;71:313–317. [Google Scholar]
- Løken T, Barlow R M. Border disease in Norway. Acta vet. scand. 1981;22:137–139. doi: 10.1186/BF03547215. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Matthews R E F. Classification and nomenclature of viruses. Inter-virology. 1979;12:129–296. doi: 10.1159/000149081. [DOI] [PubMed] [Google Scholar]
- Plant J W, Acland H M, Gard G P. A mucosal disease virus as a cause of abortion, hairy birth coat and unthriftiness in sheep. 1. Infection of pregnant ewes and observations on aborted foetuses and lambs dying before one week of age. Aust. vet. J. 1976;52:57–63. doi: 10.1111/j.1751-0813.1976.tb13855.x. [DOI] [PubMed] [Google Scholar]
- Sands J J, Harkness J W. The distribution of antibodies to Border disease virus among sheep in England and Wales. Res. Vet. Sci. 1978;25:241–242. doi: 10.1016/S0034-5288(18)32987-4. [DOI] [PubMed] [Google Scholar]
- Saxegaard F, Bratberg B, Ek N. Isolation and identification of bovine viral diarrhea/mucosal disease virus (BVD/MD Virus) from an atypical case resembling malignant catarrhal fever (MCF) Acta vet. scand. 1971;12:601–603. doi: 10.1186/BF03547728. [DOI] [PMC free article] [PubMed] [Google Scholar]
- George T D. A survey of sheep throughout Australia for antibody to parainfluenza type 3 virus and to mucosal disease virus. Aust. vet. J. 1971;47:370–374. doi: 10.1111/j.1751-0813.1971.tb09214.x. [DOI] [PubMed] [Google Scholar]
- Terlecki S. Border disease: A viral teratogen of farm animals. Vet. Ann. (Bristol) 1977;17:74–79. [Google Scholar]
- Terpstra C. Detection of Border disease antigen in tissues of affected sheep and in cell cultures by immunofluorescence. Res. Vet. Sci. 1978;25:350–355. doi: 10.1016/S0034-5288(18)32952-7. [DOI] [PubMed] [Google Scholar]
- Terpstra C. Border disease: Virus persistence, antibody response and transmission studies. Res. Vet. Sci. 1981;30:185–191. doi: 10.1016/S0034-5288(18)32579-7. [DOI] [PubMed] [Google Scholar]
- Vantsis J T, Linklater K A, Rennte J C, Barlow R M. Experimental challenge infection of ewes following a field outbreak of Border disease. J. comp. Path. 1979;89:331–339. doi: 10.1016/0021-9975(79)90022-7. [DOI] [PubMed] [Google Scholar]
- Vantsis J T, Barlow R M, Gardiner A C, Linklater K A. The effects of challenge with homologous and heterologous strains of Border disease virus on ewes with previous experience of the disease. J. comp. Path. 1980;90:39–45. doi: 10.1016/0021-9975(80)90026-2. [DOI] [PubMed] [Google Scholar]
- Vantsis J T, Rennie J C, Gardiner A C, Wells P. W.., Barlow R M, Martin W B. Immunization against Border diseases. J. comp. Path. 1980;90:349–354. doi: 10.1016/0021-9975(80)90002-X. [DOI] [PubMed] [Google Scholar]