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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 2021 Jan 23;22(3-4):403–408. doi: 10.1186/BF03548665

The Immediate Effect of HCG Upon Plasma Testosterone Levels in the Bull

Den øyeblikkelige effekt av HCG på plasma testosteron nivå hos okse

A Sundby 1,
PMCID: PMC8300462  PMID: 7344530

Abstract

No effect of HCG upon the plasma testosterone level in 16 bulls was seen the first 5 or 15 min after injection. In 8 bulls receiving 750 or 1500 i.u. HCG by intravenous injection a lag time of 30 min occurred before plasma testosterone response could be measured. The high plateau level of plasma testosterone concentration was reached approximately 1 h after injection.

Following intramuscular injection of 750 i.u. or 1500 i.u. HCG a lag time of 45–60 min was observed for the testicular response measured as elevated plasma testosterone level. The high plateau levels of plasma testosterone in these bulls were reached approximately 1½ h post injection.

Keywords: bull, HCG, immediate effect, plasma testosterone

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Footnotes

The investigation was financially supported by the Agricultural Research Council of Norway.

References

  1. Andresen Ø. 5α-androstenone in peripheral plasma of pigs, diurnal variation in boars, effects of intravenous HGG administration and castration. Acta endocr. (Kbh.) 1975;78:385–391. doi: 10.1530/acta.0.0780385. [DOI] [PubMed] [Google Scholar]
  2. Bartke A, Steele R E, Musto N, Caldwell B V. Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology. 1973;92:1223–1227. doi: 10.1210/endo-92-4-1223. [DOI] [PubMed] [Google Scholar]
  3. Boyden T W, Pamenter R W, Siluert M A. Testosterone secretion by the isolated canine testis after controlled infusions of HCG. J. Reprod. Fertil. 1980;59:25–30. doi: 10.1530/jrf.0.0590025. [DOI] [PubMed] [Google Scholar]
  4. Brinck-Johnsen T, Eik-Nes K B. Effect of human chorionic gonadotropin on the secretion of testosterone and 4-androstene-3, 17-dione by the canine testis. Endocrinology. 1957;61:176–683. doi: 10.1210/endo-61-6-676. [DOI] [PubMed] [Google Scholar]
  5. DePalatis L, Moore J, Falvo R E. Plasma concentrations of testosterone and LH in the male dog. J. Reprod. Fertil. 1978;52:201–207. doi: 10.1530/jrf.0.0520201. [DOI] [PubMed] [Google Scholar]
  6. Eik-Nes K B. Factors influencing the secretion of testosterone in the anaesthetized dog. Ciba Found. Golloq. Endocrinol. (Proc) 1967;16:120–136. [Google Scholar]
  7. Foster D L, Mickelson I H, Ryan K D, Coon G A, Drongowski R A, Holt J A. Ontogeny of pulsatile luteinizing hormone and testosterone secretion in male lambs. Endocrinology. 1978;102:1137–1146. doi: 10.1210/endo-102-4-1137. [DOI] [PubMed] [Google Scholar]
  8. Katongole, C. B., F. Naftolin & R. V. Short: Relationship between blood levels of luteinizing hormone and testosterone in bulls and the effect of sexual stimulation. J. Endocr. 1971, 50, 457– 466. [DOI] [PubMed]
  9. Katongole C B, Short R V, Naftolin F. Plasma luteinizing hormone and testosterone in the ram. J. Endocr. 1972;52:52–111. [PubMed] [Google Scholar]
  10. Lincoln G A. Plasma testosterone profiles in male macropodid marsupials. J. Endocr. 1978;77:347–351. doi: 10.1677/joe.0.0770347. [DOI] [PubMed] [Google Scholar]
  11. Moor B C, Younglai E V. Variations in peripheral levels of LH and testosterone in adult male rabbits. J. Reprod. Fert. 1975;42:259–266. doi: 10.1530/jrf.0.0420259. [DOI] [PubMed] [Google Scholar]
  12. Purvis K, Illius A W, Haynes N B. Plasma testosterone concentrations in the ram. J. Endocr. 1974;61:231–253. doi: 10.1677/joe.0.0610241. [DOI] [PubMed] [Google Scholar]
  13. Rowe P H, Hopkinson C R N, Shenton J C, Glover T D. The secretion of LH and testosterone in the rabbit. Steroids. 1975;25:313–321. doi: 10.1016/0039-128X(75)90089-6. [DOI] [PubMed] [Google Scholar]
  14. Rowe P H, Lincoln G A, Racey P A, Lehane J, Stephenson M J, Shenton J C, Glover T D. Temporal variations of testosterone levels in the peripheral blood plasma of men. J. Endocr. 1974;61:63–73. doi: 10.1677/joe.0.0610063. [DOI] [PubMed] [Google Scholar]
  15. Sand T, Torjesen P A. Dextran-coated charcoal used in the radioimmunoassay of human pituitary luteinizing hormone. Acta endocr. 1973;73:444–454. doi: 10.1530/acta.0.0730444. [DOI] [PubMed] [Google Scholar]
  16. Sanwal P C, Sundby A, Edqvist L E. Diurnal variation of peripheral plasma levels of testosterone in bulls measured by a rapid radioimmunoassay procedure. Acta vet. scand. 1974;15:90–99. doi: 10.1186/BF03547496. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Sundby A. The immediate effect of HGG upon plasma testosterone levels in the bull. Acta vet. scand. 1981;22:403–408. doi: 10.1186/BF03548665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Sundby, A. & A. Farahat: Plasma testosterone in bulls: Response to various doses of HGG and PMSG. Acta endocr. 1978, 88, 793– 800. [PubMed]
  19. Sundby A, Torjesen P A. Plasma levels of testosterone in bulls: Response to repeated HCG injections. Acta endocr. 1978;88:787–792. doi: 10.1530/acta.0.0880787. [DOI] [PubMed] [Google Scholar]
  20. Sundby, A. & W. Velle: Plasma concentration of testosterone in young bulls in relation to age, rate of weight gain and stimulation with human chorionic gonadotropin. J. Endocr. 1980, 86, 465– 469. [DOI] [PubMed]
  21. Sundby A, Tollman R, Velle W. Long-term effect of HCG on plasma testosterone in bulls. J. Reprod. Fertil. 1975;45:249–254. doi: 10.1530/jrf.0.0450249. [DOI] [PubMed] [Google Scholar]
  22. Thibier M. Diurnal testosterone and 17α-hydroxyprogesterone in peripheral plasma of young post-pubertal bulls. Acta endocr. 1976;81:623–634. [PubMed] [Google Scholar]
  23. Wilson M I, Brown G M, Wilson D. Annual and diurnal changes in plasma androgen and Cortisol in adult male squirrel monkeys (Saimiri sciureus) studied longitudinally. Acta endocr. 1978;87:424–434. doi: 10.1530/acta.0.0870424. [DOI] [PubMed] [Google Scholar]

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