We thank Ravnskov [1] for his interest in our recent publication [2]. In our study, low-density lipoprotein cholesterol (LDL-C) and Apolipoprotein B-100 (ApoB) almost doubled in young, healthy women when they followed the ketogenic low-carbohydrate high-fat (LCHF) diet. According to the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) Guidelines for the management of dyslipidaemias [3] “…there is no longer an ‘LDL-C hypothesis’, but established facts that increased LDL-C values are causally related to atherosclerotic cardiovascular disease, and that lowering LDL particles and other ApoB-containing lipoproteins as much as possible reduces cardiovascular events.” Therefore, we think it is reasonable to conclude that the alterations in blood lipids reported in our study should be a cause for concern in young women following this kind of LCHF diet.
Author Contributions
Writing—original draft preparation, J.B., M.E., N.R.T.D. and A.S. All authors have read and agreed to the published version of the manuscript.
Funding
This work was supported by P.Håkansson’s Foundation, Eslöv, Sweden, and by Magnus Bergvall’s Foundation, grant number 2014-00411, Sweden. The authors have not received any funding or benefits from commercial organizations.
Conflicts of Interest
The authors declare no conflict of interest.
Footnotes
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References
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