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Associations between genetically predicted coffee consumption and cardiovascular diseases. CI indicates confidence interval; OR, odds ratio. The I2 statistic represents heterogeneity across estimates of used SNPs. Aortic aneurysm includes abdominal and thoracic aortic aneurysm in FinnGen. Data for non-rheumatic valve diseases was used to replicate the association for aortic valve stenosis in FinnGen.
