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. 2021 Jun 3;52(8):2680–2684. doi: 10.1161/STROKEAHA.121.034747

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© 2021 The Authors.

Stroke is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure. — Forest plot showing the main Mendelian randomization estimates for the association between genetically proxied lipid traits and type 2 diabetes (T2D) liability with risk of ischemic stroke in African and European ancestry populations. Estimates represent odds ratios and their 95% CIs for ischemic stroke risk per 1 SD increase in genetically predicted levels of the exposure. HDL-C indicates high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; and TG, triglycerides.