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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 1980 Sep 1;21(3):380–388. doi: 10.1186/BF03546870

Quantitative Comparisons of Acidic Prealbumin (Pr) Phenotypes in Horses

Kvantitative sammenligninger au sure prealbumin (Pr) fenotyper hos bester

Nils Ek 1,, Mikael Brænd 1
PMCID: PMC8317704  PMID: 7446321

Abstract

Comparisons of Pr protein amounts in horse sera have been performed using Mancini et al.’s (1965) immunodiffusion technique. Relative values against a chosen standard of 100 % were determined for a total of 435 horses.

There was considerable variation between horses, the highest Pr value being 125 % and the lowest 50 % of the standard. In animals of the same Pr phenotype the mean Pr values were significantly higher (P < 0.001) in foals than in mares. In Norwegian Trotter horses the Pr value of Pr NN animals was significantly higher than that of Pr SS phenotypes, whereas the mean Pr values of Pr SS was significantly higher than that of Pr UU Warmblood Trotter horses, the Pr value of Pr SS being 90 % and the Pr-UU 80 % of that of Pr NN.

No difference between sexes with regard to Pr values was found.

Keywords: horse, serum, Pr phenotypes, relative Pr quantities

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References

  1. Brœnd M. Genetics of horse acidic prealbumins. Genetics. 1970;65:495–503. doi: 10.1093/genetics/65.3.495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ek N. The characterization of equine prealbumin (Pr) proteins by antigen-antibody crossed electrophoresis. Acta vet. scand. 1979;20:180–190. doi: 10.1186/BF03546610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ek, N.: Quantitation of the Pr protein in equine serum in diseases. In preparation. 1980.
  4. Fagerhol M K. Quantitative studies of the inherited variants of serum α1-antitrypsin. Scand. J. clin. Lab. Invest. 1969;23:97–103. doi: 10.3109/00365516909078092. [DOI] [PubMed] [Google Scholar]
  5. Ganrot P O, Laurell C-B, Eriksson S. Obstructive lung disease and trypsin inhibitors in α1-antitrypsin deficiency. Scand. J. clin. Lab. Invest. 1967;19:205–208. doi: 10.3109/00365516709090627. [DOI] [PubMed] [Google Scholar]
  6. Mancini G, Carbonaro A O, Heremans J F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965;2:235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  7. Matthews, A. G.: The identification and characterisation of the major antiproteases in equine serum and an investigation of their role in the onset of chronic obstructive pulmonary disease (COPD). Equine vet. J. 1979 a, 11, 177–182. [DOI] [PubMed]
  8. Matthews, A. G.: The nature of the prealbumin “esterases” of horse serum. Anim. Blood Grps biochem. Genet. 1979 b, 10, 181–184. [DOI] [PubMed]
  9. Scott, M.: Prealbumins in the Arab Horse; a model for a better interpretation of the system. XVI Int. Conf. Anim. Blood Groups Biochem. Polym., 158 (Abstr.) USSR, Leningrad, August 14–18, 1978.

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