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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 1980 Sep 1;21(3):305–311. doi: 10.1186/BF03546860

Antipenicillinase in the Serum of Dairy Cows

Antipenicillinase i serum hos kyr

Ø Lie 1,2,, H Solbu 1,2
PMCID: PMC8317705  PMID: 6969539

Abstract

Serum from dairy cows was tested for inhibitory effect on penicillinase from a penicillin-resistant Staphylococcus aureus strain of mastitic origin. Among cows with subclinical mastitis caused by penicillin-resistant S. aureus there was a significantly higher frequency of individuals with penicillinajse-inhibiting serum than among healthy cows. Among the subclinical cases, a foregoing penicillin treatment of clinical mastitis appeared to increase the serum antipenicillinase activity.

Keywords: serum antipenicillinase, penicillin resistance, Staphylococcus aureus, bovine mastitis

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References

  1. Fossum K. Proteolytic enzymes and biological inhibitors. VI. Antibodies in animal sera against the proteinase of Gorynebacterium pyogenes. Acta path, microbiol. scand. 1071;79:117–122. [PubMed] [Google Scholar]
  2. Gudding R. An agar diffusion method for the determination of antibodies against Staphylococcus aureus deoxyribonuclease. Acta vet. scand. 1977;18:480–493. doi: 10.1186/BF03548411. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Housewright R D, Henry R J. Studies on penicillinase. III. The effect of antipenicillinase on penicillin resistant organisms. J. Bact. 1947;53:241–247. doi: 10.1128/JB.53.2.241-247.1947. [DOI] [PubMed] [Google Scholar]
  4. Lie Ø. Genetic analysis of some immunological traits in young bulls. Acta vet. scand. 1979;20:372–386. doi: 10.1186/BF03546599. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Pollock, M. R.: Stimulating and inhibiting antibodies for bacterial penicillinase. Immunology 1964, 7, 707–723. [PMC free article] [PubMed]
  6. Richmond, M. H.: Enzyme/antiserum interactions of β-lactamiases. In Immunochemistry of Enzymes and their Antibodies. M. R. J. Salton (ed.). John Wiley & Sons, New York 1977.
  7. Sandvik Ø. The occurrence of antibodies against staphylococcal de-oxyribonucleases in blood sera from different species. Acta vet. scand. 1974;15:631–635. doi: 10.1186/BF03547232. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sandvik O. The occurrence of antibodies against staphylococcal de-oxyribonucleases in bovine milk. Acta vet. scand. 1975;16:140–142. doi: 10.1186/BF03546704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Solbu, H.: Breeding for improved disease resistance, with special emphasis on a practical method of collecting data. 1978. EAAP, 29th Ann. Meeting, Stockholm, C/1.03, 8 pp.
  10. Workman R G, Farrar W E., jr Activity of penicillinase in Staphylococcus aureus as studied by the iodometric method. J. infect Dis. 1970;121:433–437. doi: 10.1093/infdis/121.4.433. [DOI] [PubMed] [Google Scholar]

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