Abstract
The effect of vitamin E on the toxicity of cadmium (Cd) in Cd-sensitive Staphylococcus aureus 3719– was studied. The addition of vitamin E into the liquid growth medium resulted in a shortened lag phase of growth in Gd-stressed S. aureus 3719–. It is suggested that the decrease observed in the length of the lag phase is due to the antioxidative effect of vitamin E which indicates that Cd together with hydrogen peroxide produced by the bacterium may induce an oxidative damage in staphylococcal cells.
Keywords: D-alpha tocopherol, antioxidative effect, lag phase, oxidative damage
Sammanfattning
Effekten av E-vitamin på kadmiums (Cd) toxicitet på en Cd-kånslig Staphylococcus aureus 3719— undersöktes. Tillsatsen av E-vitamin till det flytande nåringssubstratet fórkortade lagfasen i den Cd-belastade S. aureus 3719–. Det år mójligt att den observerade fórminskningen i långden av lagfasen beror på den antioxidativa effekten av E-vitamin. Detta tyder på att Cd tillsammans med våteperoxid producerad av bakterier kunde fórorsaka en oxidativ skada på stafylokockceller.
Full Text
The Full Text of this article is available as a PDF (450.8 KB).
References
- Albert, A.: Selective Toxicity – The Physico-Chemical Basis of Therapy. 5th Ed., Chapman and Hall, London, England 1973.
- Korkeala H., Sankari S. The effect of catalase on the toxicity of cadmium in cadmium-sensitive and cadmium-resistant Staphylococcus aureus. Acta vet. scand. 1980;21:209–223. doi: 10.1186/BF03546884. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Martius C., Müller K. Tokopherol und Tokopherylchin on als Wachstumsfaktoren für Fusiformis nigrescens. (Tocopherol and tocopheryl quinone as growth factors in Fusiformis nigrescens) Biochem. Z. 1964;340:320. [PubMed] [Google Scholar]
- Pamini C. F., Ugolini A. Antibiogrammi di stafilococchi e tocoferolo. (The antibiogram of some Staphylococcus strains and tocopherol) Aggiorn. pediat. 1961;12:615–620. [Google Scholar]
- Stephenson, M.: Bacterial Metabolism. The M.I.T. Press, Cambridge, Massachusetts, USA, and London, England 1966.