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. 2021 Mar 11;144(6):1799–1818. doi: 10.1093/brain/awab085

Table 1.

Clinical and theoretical homologues

Neurological syndrome Clinical sign Synthetic lesion Functional role
Cerebellar Pendular reflexes λ Smoothness of random fluctuations
Dysmetria λ
Corticospinal Brisk reflexes Π Precision (inverse variance) of likelihood distributions
Preserved coordination Π
Parkinsonian Slow movements γ Precision (inverse temperature) of policy priors
Small amplitude movements γ
Delay in movement initiation γ
Executive Impaired ‘immediate recall’ A Precision (inverse temperature) of empirical (hierarchical) priors