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. 1979 Dec 1;20(4):469–476. doi: 10.1186/BF03546574

Colostral Trypsin-Inhibitor Capacity in Different Animal Species

Trypsin-inhiberande kapacitet av kolostrum hos olika djurslag

M Sandholm 1,✉, T Honkanen-Buzalski 1
PMCID: PMC8322878  PMID: 546206

Abstract

Colostral trypsin-inhibitor capacity was monitored during the first two weeks from parturition. The colostrum of the mare, sow, cow and ewe showed high antitrypsin activity at parturition, decreasing to about one hundredth during the first week. Canine milk remained on a relatively high antitrypsin level, and human milk was poor in antitrypsin from childbirth. The antitrypsin content seems to parallel the known changes in the colostral immunoglobulin levels of different species. The role of antitrypsin in protection of immunoglobulins from proteolytic damage during passive transfer of immunity to the newborn is obvious.

Keywords: colostrum, trypsin inhibitor, protease inhibitors, colostral albumin

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