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. 1979 Jun 1;20(2):289–305. doi: 10.1186/BF03546620

Selenium and Vitamin E Deficiency in Pigs

II. Influence on Plasma Selenium, Vitamin E, Asat and Alat and on Tissue Selenium

Selen- og vitamin E mangel hos svin. II. Indflydelse på Se og Vit. E plasma- og Se vævsværdier samt plasma ASAT og ALAT

M G Simesen 1,2,3,4,✉, H E Nielsen 1,2,3,4, V Danielsen 1,2,3,4, G Gissel-Nielsen 1,2,3,4, W Hjarde 1,2,3,4, T Leth 1,2,3,4, A Basse 1,2,3,4
PMCID: PMC8322908  PMID: 484408

Abstract

The effect of dietary selenium (Se) and vitamin E (Vit. E) in pigs on Se and Vit. E in plasma and on Se in tissue from liver, heart, m. long, dorsi and m. psoas major was studied; and furthermore was the influence on the enzymes ASAT and ALAT studied.

Two levels of Se were used, 0.03 and 0.06 mg Se per kg feed. Within each Se level 2 levels of Vit. E were used, 15 and 45 i. u. per kg feed. This resulted in 4 groups: 1. low Se and low Vit. E; 2. low Se and high Vit. E; 3. high Se and low Vit. E; 4. high Se and high Vit. E.

Ten% of all pigs fed low Se, and 4% of the pigs fed low Se and high Vit. E diet died with severe symptoms of Se deficiency. None of the pigs fed the high Se diet died with such symptoms. Plasma Se determinations have been shown to indicate the Se status in pigs almost as accurately as liver Se determination. ASAT and ALAT enzyme determinations were not of any diagnostic value.

There was a good agreement between dietary Vit. E level and the corresponding levels in plasma. Oxidized herring oil seems to enhance the Vit. E need.

Keywords: selenium, vitamin E, hepatosis dietetic a, mulberry heart disease, selenium in plasma and tissue, vitamin E in plasma, ASAT, ALAT, pigs

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Footnotes

This investigation was supported by a grant from the Danish Agricultural and Veterinary Research Council.

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