Graphical Abstract
Feeding the growing population in a sustainable, environmentally-friendly manner will require implementation of management strategies and metabolic effectors that facilitate efficient protein deposition in livestock (Dunshea et al., 2016). Beta adrenergic receptor ligands fed to cattle improve live animal performance that translates into positive effects on muscle protein accretion and carcass parameters (Bittner et al., 2016; Bittner et al., 2017; DeClerck et al., 2020; Lockard et al., 2020). A recent review discusses the differences in the β-ligands, the receptors they interact with and the resulting tissue outcomes (Dilger et al., 2021).
References
- Bittner, C. J., Crawford G. I., Berger L. L., Holt S., Pritchard R. R., Platter W. J., Van Koevering M. T., Pyatt N. A., and Erickson G. E.. . 2016. Effect of ractopamine hydrochloride (Optaflexx) dose and duration on growth performance and carcass characteristics of finishing steers. J. Anim. Sci. 94:5382–5392. doi: 10.2527/jas.2016-0807. [DOI] [PubMed] [Google Scholar]
- Bittner, C. J., Greenquist M. A., Burken D. B., Shreck A. L., MacDonald J. C., Klopfenstein T. J., Platter W. J., Van Koevering M. T., Pyatt N. A., and Erickson G. E.. . 2017. Evaluation of ractopamine hydrochloride (Optaflexx) on growth performance and carcass characteristics of finishing steers across different feeding durations. J. Anim. Sci. 95:485–498. doi: 10.2527/jas.2016.0806. [DOI] [PubMed] [Google Scholar]
- DeClerck, J. C., Lucherk L. W., Reeves N. R., Miller M. F., Bernhard B. C., and Rathmann R. J.. . 2020. Influence of ractopamine hydrochloride and days on feed on feedlot performance and red meat yield in thin cull beef cows targeted for a lean market. Transl. Anim. Sci. 4:170–181. doi: 10.1093/tas/txz184. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dilger, A. C., Johnson B. J., Brent P., and Ellis R. L.. . 2021. Comparison of beta-ligands used in cattle production: structures, safety, and biological effects. J Anim Sci. 99:skab094. doi: 10.1093/jas/skab094. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dunshea, F. R., D’Souza D. N., and Channon H. A.. . 2016. Metabolic modifiers as performance-enhancing technologies for livestock production. Animal Frontiers. 6:6–14. doi: 10.2527/af.2016-0038. [DOI] [Google Scholar]
- Lockard, C. L., Richards C. J., Lockard C. G., Youngers M., Woolsoncroft M. A., Husz T. C., Wilson B. K., Goad C. L., Jackson T. A., Step D. L., . et al. 2020. Growth, performance, and carcass characteristics of feedlot Holstein steers fed ractopamine hydrochloride. Transl. Anim. Sci. 4:102–117. doi: 10.1093/tas/txz157. [DOI] [PMC free article] [PubMed] [Google Scholar]