Correction to: Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega‑3 polyunsaturated fatty acid eicosapentaenoic acid

Correction to: Cancer Chemotherapy and Pharmacology 10.1007/s00280-020-04157-2

In the original publication of the article, curves, more data point and lines were missing in the Fig. 2A. The corrected Fig. 2 is given below. The original article has been corrected.

Fig. 2.

COX expression mediates EPA sensitivity of CRC cells in vitro. a MTT cell viability assay curves for the effect of EPA on MC38 (closed circles) and MC38r mouse CRC cells (open circles). Data represent the mean ± SEM % growth compared to untreated control cells for three independent replicates for each mouse CRC cell line. b Western blot analysis of COX isoform protein expression in MC38 and MC38r mouse CRC cells. c PGE₂ levels in medium conditioned by MC38 and MC38r cells for 24 h. Data compared with Student’s t test. d Western blot analysis of COX isoform protein expression in CT26 and COX^low-CT26 mouse CRC cells. e PGE₂ levels in medium conditioned by CT26 and COX^low-CT26 mouse CRC cells for 24 h. Data compared with Student’s t test. f MTT cell viability assay curves for the effect of EPA on CT26 (closed circles) and COX^low-CT26 mouse CRC cells (open circles). Data represent the mean ± SEM % growth compared to untreated control cells for three independent replicates for each mouse CRC cell line. Two-way ANOVA confirmed a significant increase in EPA sensitivity of COX^low-CT26 cells compared with CT26 mouse CRC cells (p = 0.03)