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AJNR: American Journal of Neuroradiology logoLink to AJNR: American Journal of Neuroradiology
. 1984 Mar-Apr;5(2):181-3.

Iohexol versus Metrizamide for Lumbar Myelography: Double-Blind Trial

Trygve O Gabrielsen 1, Stephen S Gebarski 1, James E Knake 1, Joseph T Latack 1, Peter J Yang 1, Julian T Hoff 2
PMCID: PMC8332542

Abstract

Lumbar myelography was performed in 50 patients; 25 received iohexol (an investigational aqueous contrast agent) and 25 received metrizamide. The two media produced radiographs of equal quality. However, iohexol is stable in solution, while metrizamide is not. Further, markedly less morbidity resulted from iohexol. These features indicate that iohexol may be superior to metrizamide as a contrast agent for lumbar myelography.

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