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AJNR: American Journal of Neuroradiology logoLink to AJNR: American Journal of Neuroradiology
. 1993 Mar-Apr;14(2):426-9.

Proton MR spectroscopic characteristics of a presumed giant subcortical heterotopia.

M Castillo 1, L Kwock 1, J Scatliff 1, S Gudeman 1, R Greenwood 1
PMCID: PMC8332958  PMID: 8456723

Abstract

A newborn presented with a mass replacing the left cerebral hemisphere. Although the internal signal characteristics of the lesion were suggestive of disorganized gray and white matter, a true neoplasia such as a ganglioglioma could not be totally excluded. Biopsy is not recommended in these cases since the results may be misleading. Proton MR spectroscopy was used; this technique also suggested the hamartomatous nature of the lesion. Based on the clinical course and the imaging features, conservative therapy and observation were undertaken instead of surgery. At 6 months of age, the patient is stable and the lesion is unchanged.

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