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Hormone replacement with 17β-Estradiol reversed ovariectomy-induced visceral hypersensitivity in conventional females
(A) Experimental timeline.
(B) 17β-Estradiol reversed ovariectomy-induced visceral hypersensitivity in conventional mice.
∗p ≤ 0.05, ∗∗p ≤ 0.01 ovariectomized with estradiol versus placebo group. n = 13–14 per group. Data presented as Mean ± SEM. n = 13–14 per group. VMR, visceromotor response; OVX, ovariectomy.
