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AJNR: American Journal of Neuroradiology logoLink to AJNR: American Journal of Neuroradiology
. 1998 Sep;19(8):1437-40.

Spontaneous labyrinthine hemorrhage in sickle cell disease.

R E Whitehead 1, C B MacDonald 1, E R Melhem 1, L McMahon 1
PMCID: PMC8338684  PMID: 9763373

Abstract

We report the clinical and MR imaging findings in two African-American patients with manifestations of sickle cell disease affecting the inner ear. Both suffered sudden-onset sensorineural hearing loss and vestibular symptoms, and both had high labyrinthine signal on T1-weighted MR images attributed to labyrinthine hemorrhage. Follow-up studies of the first patient revealed a decrease in abnormal vestibular signal. Careful attention to the labyrinth on T1-weighted MR images can reveal vestibulocochlear clinical findings in sickle cell patients, with important implications for management and prognosis.

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