Computed tomography images and photographs of the left breast over the treatment course. Abbreviations: AC, doxorubicin + cyclophosphamide; Cap, capecitabine; CNB, core needle biopsy; Lap, lapatinib; PD, progressive disease; PER + HER + DTX, pertuzumab + trastuzumab + docetaxel; T‐DM1, ado‐trastuzumab emtansine; T‐DXd, fam‐trastuzumab deruxtecan; VNR, vinorelbine.