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. 2021 Jul 6:taab104. doi: 10.1093/jtm/taab104

Neutralization of Beta and Delta variant with sera of COVID-19 recovered cases and vaccinees of inactivated COVID-19 vaccine BBV152/Covaxin

Pragya D Yadav 1,2,, Gajanan N Sapkal 2,2, Raches Ella 3, Rima R Sahay 4, Dimpal A Nyayanit 5, Deepak Y Patil 6, Gururaj Deshpande 7, Anita M Shete 8, Nivedita Gupta 9, V Krishna Mohan 10, Priya Abraham 11, Samiran Panda 12, Balram Bhargava 13
PMCID: PMC8344909  PMID: 34230972

Abstract

SARS-CoV-2 variant of concern mainly Delta and Beta is global public health concern due to its impact on existing vaccines. Here, we assessed the neutralization of sera from COVID-19 recovered cases and BBV152 vaccinees against Beta and Delta variants. BBV152 vaccine found to confer significant protection against both the variants.

Keywords: neutralization, vaccine efficacy, Delta, Beta, SARS-CoV-2


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