Figure 16.

Cytochrome domain types with surface-exposed heme propionates (red sticks) frequently found in DET-capable multi-cofactor enzymes. (a) Heme b domain of Gallus gallus sulfitef oxidase (PDB: 1SOX) that structurally resembles b₅-type cytochrome or b₂ cytochrome domain of L-lactate dehydrogenase; (b) heme b domain of Neurospora crassa cellobiose dehydrogenases (PDB: 4QI7), which can be also found in PQQ-pyranose dehydrogenases; (c) heme c₅₅₁ domain of Pseudomonas putida PQQ-dependent type II alcohol dehydrogenase (PDB: 1YIQ).