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. 2021 Aug 5;59:314–320. doi: 10.1016/j.breast.2021.08.003

Table 4.

Multivariate cox proportional hazard model to predict disease-specific survival.

Variable Hazards Ratio 95 % Confidence Interval P-Value
Age (continuous) 1.01 (1.01 1.02) <0.001
Race
White Ref
Black 1.16 (1.08 1.25) <0.001
Other 0.99 (0.89 1.10) 0.961
nSES
Low 1.34 (1.25 1.44) <0.001
Middle 1.20 (1.13 1.29) <0.001
High Ref
Marital Status
Married/Partnered Ref
Separated/divorced 1.15 (1.06 1.24) 0.001
Single 1.15 (1.07 1.24) <0.001
Unmarried/Domestic Partner 0.94 (0.57 1.57) 0.828
Widowed 1.29 (1.19 1.40) <0.001
Year of Diagnosis
2010 Ref
2011 1.00 (0.92 1.09) 0.919
2012 0.99 (0.90 1.08) 0.758
2013 0.97 (0.89 1.06) 0.533
2014 0.87 (0.79 0.97) 0.009
2015 0.89 (0.79 0.99) 0.049
2016 0.84 (0.72 0.99) 0.039
Insurance
Insured Ref
Uninsured 1.43 (1.26 1.63) <0.001
Medicaid 1.21 (1.13 1.30) <0.001
Grade
Well-differentiated Ref
Moderately differentiated 1.40 (1.25 1.58) <0.001
Poorly differentiated 2.03 (1.80 2.29) <0.001
Undifferentiated 1.87 (1.39 2.51) <0.001
Breast Cancer Subtype
Luminal A Ref
Luminal B 0.78 (0.72 0.85) <0.001
HER 2 enriched 0.95 (0.85 1.05) 0.313
Triple-Negative 3.19 (2.31 2.68) <0.001
Histology
Ductal Ref
Lobular 1.26 (1.15 1.38) <0.001
Mixed (ductal and lobular) 1.07 (0.94 1.22) 0.301
Other 1.18 (1.07 1.30) 0.001
Number of Metastasis
1 Ref
≥2 1.68 (1.59 1.79) <0.001
Surgery status
No Ref
Yes 0.52 (0.49 0.56) <0.001
Radiation Therapy
No/Unknown Ref
Yes 1.09 (1.03 1.16) 0.001