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. 1978 Dec 1;19(4):549–560. doi: 10.1186/BF03547594

Ultrastructure of Colonic Epithelial Cells in Vitamin E and Selenium Deficient Pigs

Ultrastrukturelle forandringer i kolonepíteleeller ved vitamin E-og selenmangel hos gris

Jon Teige jr 18,28,✉, Per H J Nafstad 18,28
PMCID: PMC8366347  PMID: 742565

Abstract

Pigs deficient in vitamin E and selenium had a decreased contrast of the intracellular membranes compared with pigs supplemented with vitamin E and selenium. Other common changes in the deficient animals included a reduced number of microvilli, with a short and irregular appearance, numerous swollen mitochondria with empty spaces and intercellular oedema. It is suggested that these morphological changes are attributed to the insufficient supply of vitamin E and selenium, though it is not excluded that particular intestinal factors may participate in the development of the lesions.

Keywords: cellular membranes, vitamin E and selenium deficiency, colonic epithelial cells, pig

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