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. 1978 Jun 1;19(2):269–284. doi: 10.1186/BF03547632

Serum Glutathione Peroxidase Activity and Blood Selenium in Pigs

Serumgluiationperoxidas-aktivüet och blodselen hos grisar

Juhani Hakkarainen 112,212,✉, Paul Lindberg 112,212, Gösta Bengtsson 112,212, Lennart Jönsson 112,212
PMCID: PMC8366361  PMID: 696539

Abstract

Blood serum glutathione peroxidase activity and blood selenium concentration were measured in blood samples from pigs subjected to experimentally induced selenium deficiency and dietary selenium supplementation on graded levels. A highly significant correlation between blood selenium and serum GSH-Px activity in pigs, especially in selenium deficient pigs, was demonstrated. There was also a strong relationship between blood selenium concentration and serum GSH-Px activity in pigs receiving dietary selenium at graded levels. Serum GSH-Px activity exhibited an excellent close-response relationship to dietary selenium. Linear regression analysis showed that the increased serum GSH-Px activity was a function of the dietary selenium concentration. The fitness of serum in monitoring slight changes of the selenium status of pigs with help of the estimation of GSH-Px activity was discussed. The measurement of serum GSH-Px activity seems to provide a useful and rapid means for defining selenium requirements and for identifying selenium deficiency in growing pigs.

Keywords: serum glutathione peroxidase, blood selenium, dietary selenium, pigs

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