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. 2021 Jul 16;13(7):e16429. doi: 10.7759/cureus.16429

Table 2. Univariate and multivariate analyses for progression-free survival.

BMI, body mass index; HR, hazard ratio; NACT; neoadjuvant chemotherapy; NLR, neutrophil-to-lymphocyte ratio; PDS; primary debulking surgery; FIGO: International Federation of Gynecology and Obstetrics; CA-125: cancer antigen-125; LG includes endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma, and low-grade serous carcinomas; HG includes high-grade serous carcinomas.

Characteristics Category Univariate Multivariate
P-value HR (95% CI) P-value
Age ≥47 vs. <47 years 0.894 0.60 (0.22-1.63) 0.316
Parity Multiparous vs. nulliparous 0.013 4.63 (1.39-15.39) 0.012
Menopausal status Postmenopause vs. premenopause 0.632 - -
BMI ≥24.0 vs. <24.0 kg/m2 0.990 - -
Serum CA-125 levels ≥112.0 vs. <112.0 U/mL 0.401 1.30 (0.36-4.68) 0.687
Comorbidity Yes vs. No 0.069 2.77 (0.91-8.40) 0.072
Upfront primary treatment NACT vs. PDS 0.366 0.71 (0.23-2.15) 0.539
Ascites  Yes vs. No 0.294 0.91 (0.34-2.40) 0.848
FIGO stage Advanced vs. early 0.296 1.19 (0.25-5.74) 0.824
Surgical debulking status  Optimal vs. suboptimal 0.952 - -
Histological subtype HG vs. LG 0.958 - -
Pretreatment NLR ≥2.23 vs. <2.23 years 0.033 2.43 (0.95-6.27) 0.065