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. 2021 Aug 16;9:e11984. doi: 10.7717/peerj.11984

Figure 5. Analgesic responsiveness of each outcome measure in cats with oral cancer.

Figure 5

Responsiveness testing of outcome measures in cats with oral cancers via: (A) UFEPS/VET; EVF testing at the (B) ipsilateral and (C) contralateral intermandibular sites, (D) ipsilateral maxilla, and (E) right metacarpus; and (F) COBO aesthesiometer testing. Cats had altered thresholds in orofacial pain measurements after buccal administration of buprenorphine; thresholds returned to baseline by the next morning. Significantly increased mechanical sensory thresholds at the ipsilateral intermandibular sites were observed 30 min after buprenorphine administration, and similarly, the length of COBO filament required to elicit response became shorter (i.e., the pressure threshold increased) with buprenorphine administration (P = 0.04 and 0.02, respectively, see Table S7).