Notice of Retraction: Acharya P, Engel JC, Correia MA (2009) Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: A consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2α (eIF2α)-kinase (PERK) and general control nonderepressible-2 eIF2α kinase (GCN2), and global translational shutoff. Mol Pharmacol 76(3):503–515; DOI: https://doi.org/10.1124/mol.109.056002.

At the request of the corresponding author and investigator at the University of California, San Francisco, and in consultation with Molecular Pharmacology, this paper has been retracted. It was found there was improper manipulation, reuse, and analyses represented by Figs. 1A, 3A, 4A, 4C, 5, and 7.