Figure 1.

Blood glucose, insulin, total GIP and total GLP-1 concentration during oral oil tolerance tests with saline or CCK agonist treatment

Blood glucose (A and B), insulin (C and D), total GIP (E and F), and total GLP-1 (G and H) concentration during oral oil tolerance tests 1 (A, C, E, and G) and 2 (B, D, F, and H) in 13-week-old male WT mice (n = 6 mice in each group). Test 1 is a tolerance test in which the same dose of oil is orally administered and Test 2 is a tolerance test in which the same dose of olive oil is orally administered. White circles indicate olive oil (13.3 mL/kg body weight). Gray circles indicate olive oil (10 mL/kg body weight). Black circles indicate mixed oil. Dot line and solid line indicate saline (control) and CCK agonist treatment group, respectively. Data indicate the mean ± SEM. Statistical significance was calculated by One-way ANOVA with Tukey’s test using SPSS statistics. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. 0 min. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001 vs. Saline + Olive oil.^†P < 0.05, ^††P < 0.01, ^†††P < 0.001 vs. CCK agonist + Olive oil.