Table 1.

Polymorphisms in NF-κB genes and genes of NF-κB signaling molecules.

Gene Name	Genetic Aberration	Comments	References
NFKB1	SNP_rs230521	observed in GC patients	[32]
	SNP_rs28362491 (−94 ins/del ATTG)	associated with diffuse GC, accelerate severe gastric inflammation	[33,34]
	SNP_rs4648068	increased risk of GC	[36,37]
	homozygous deletion	invasive GC, gastric atrophy in mice	[38,39]
NFKB2	homozygous deletion	gastric hyperplasia, early postnatal death	[40]
		suppressed in gastric mucosal lesions	[39]
NFKBIA	SNP_rs2233408 T/C homozygote	GC susceptibility	[41]
	SNP_rs2233408 T heterozygote	reduced GC risk in intestinal-type non-cardiac GC
	SNP_rs17103265	risk factor for gastric carcinogenesis	[42]
	SNP_rs696	cardia GC susceptibility	[43]
	SNP_rs2233406	non-cardia GC susceptibility
I ΚBKB	SNP_rs2272736 A homozygote	prolonged overall survival time	[44]
TNIP1	SNP_rs7708392	associated with GC risk	[45]
	SNP_rs10036748
MYD88	deletion, mutation	gastric mucosal damage, carcinogenesis	[46]
	L265P mutant	observed in gastric mucosa-associated lymphoid tissue (MALT) lymphomas	[47]
RIPK2	SNP_rs16900627	increased risk of intestinal GC	[48]
TLR9	SNP_rs5743836 (−1237 T/C)	associated with H. pylori-induced GC	[49]