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. 2021 Aug 27;203:564–574. doi: 10.1016/j.ymeth.2021.08.007

Table 2.

Details of overlap of spreader nodes and potential COVID19 FDA listed drugs.

Sl. No. COVID19 FDA listed Drugs DrugBank ID Drug Protein targets/Spreader nodes No. of hits
1 Hydroxychloroquine DB01611 TLR9, ACE2, CYP3A4, ABCB1 4
2 Azithromycin DB00207 CYP3A4, ABCB1 2
3 Lopinavir DB01601 CYP3A4, ABCB1 2
4 Ritonavir DB00503 CYP3A4, ABCB1 2
5 Remdesivir DB14761 R1AB_SARS2 1
6 Favipiravir DB12466 ABCB1 1
7 Darunavir DB01264 CYP3A4, ABCB1 2