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. 2021 Aug 27;203:564–574. doi: 10.1016/j.ymeth.2021.08.007

Table 10.

Role of CDK1 and NTRK1, EGFR in viral infections.

Drug Key Target Genes Level Role in viral infections
Fostamatinib CDK1 Level-1 Viruses can express some oncoproteins. Genome replication gets induced inside the hosts' cells due to some signals generated due to the interference of these proteins with CDK and CIKs function [70].
NTRK1 Level-2 NTRK1 has an active role in the immune response against viral infection [71].
EGFR Level-2 Hindrance of EGFR signalling might prevent an excessive fibrotic response to SARS-CoV.