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Serum resistin (A) and leptin (B) levels at day 30 of CIOA. Data are means ± SD from three determinations (n = 10 per group). * p < 0.05, ** p < 0.01, *** p < 0.001, one-way ANOVA. (CIOA = collagenase-induced osteoarthritis; metf = metformin; alendr = alendronate).
