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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 1975 Jun 1;16(2):297–306. doi: 10.1186/BF03546684

Electrophoretic Patterns of Serum Proteins in Blue Foxes with Special Reference to Changes Associated with Nosematosis

Elektroforetisk separasjon av serumproteiner hos blårev spesielt med henblikk på forandringene ued nosematose

S F Mohn 1,, K Nordstoga 1
PMCID: PMC8396006  PMID: 52292

Abstract

The serum proteins in 1 group of healthy breeders, 1 group of healthy pups and 4 groups of foxes suffering from various diseases were separated electrophoretically on cellulose acetate membranes. In most of the sera, the proteins were separated into 1 albumin fraction and 5 globulin fractions designated alpha1, alpha2, alpha3, beta and gamma. The mean concentrations of the total proteins and the various serum fractions in the disease groups were compared statistically with the mean values of the normal groups.

A nosematosis group was characterized by a distinct hypergammaglobulinaemia together with an increase in the total protein — and a decrease in the albumin concentrations. However, in 2 cubs recovering from nosematosis the hypergammaglobulinaemia was shown to be reversible.

In a feed intoxication group the concentration of albumin was found to be lower and the alpha3-globulin higher than the corresponding values in the healthy group. A virus hepatitis group was characterized by a decrease in the concentrations of albumin and beta-globulin and an increase in the alpha1- and alpha3-globulins. In the toxoplasmosis group the total protein and alpha1- and alpha3-globulins showed concentrations below the normal values.

Keywords: blue fox, serum proteins, nosematosis, hypergammaglobulinaemia

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