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Acta Veterinaria Scandinavica logoLink to Acta Veterinaria Scandinavica
. 1975 Sep 1;16(3):379–387. doi: 10.1186/BF03546655

Virus Inactivation by Ethylene Oxide Containing Gases

Virus inaktivering ved hjælp af etylenoxydholdige luftblandinger

Angelika Jordy 1,2, Rikke Hoff-Jørgensen 1, Annette Flagstad 1, Ebba Lund 1,
PMCID: PMC8396082  PMID: 170812

Abstract

Gases containing ethylene oxide mixed with carbon dioxide alone (Etox®) or together with methyl formate (Etoxiat®) were employed for virus treatment in a way that has been shown efficient for the killing of bacteria. A number of viruses selected for their capacity to withstand chemical or physical treatments were tested under varying conditions, including in a dried state in the presence of high amounts of organic matter (animal spillings). The viruses tested were enteroviruses, paramyxovirus (NDV), poxvirus and parvovirus, and they were all inactivated to a high degree.

Keywords: ethylene oxide, virus inactivation

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References

  1. Andrewes, Chr. & H. G. Pereira: Viruses of Vertebrates. 3rd ed. Bailliére Tindall, London 1972.
  2. Flagstad, Annette: A serological study of feline penleukopaenia virus and mink enteritis virus. Acta path, microbiol. scand. 1975. In press. [DOI] [PMC free article] [PubMed]
  3. Hoff-Jørgensen R, Lund E. Studies on the inactivation of viruses by ethylene oxide. Acta vet. scand. 1972;13:520–527. doi: 10.1186/BF03547157. [DOI] [PMC free article] [PubMed] [Google Scholar]

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