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Lactoferrin detection by surface plasmon resonance (SPR) sensor. (a) SPR on sensor chips (i. Surface modification on sensor chips or gold nanoparticles; ii. The capture of lactoferrin on the surface was tested by laser beam; iii. Concentration dependent intensity change or red shift was recorded); (b) localized surface plasmon resonance (LSPR, the slight change of the refractive index of gold nano-shell after capture of lactoferrin results in the red shift of resonant frequency).
